Mesothelioma: What is it?


Malignant Mesothelioma is the most serious of all asbestos-related diseases. It is a rare form of cancer in which malignant cells are found in the sac lining of the chest (pleura) or abdomen (peritoneum). Virtually all cases of malignant mesothelioma are attributable to asbestos exposure.

An x-ray is often the first method used in the diagnosis of mesothelioma. Although mesothelioma typically cannot be seen on an x-ray, the tumor often causes a pleural effusion, or fluid collection between the lung and chest wall. This abnormal finding is associated with shortness of breath and warrants clinical followup. For confirmation of the disease a pathology specimen from a biopsy or operation is usually required. Like most cancers, malignant mesothelioma is best treated when it is diagnosed early. Mesothelioma progresses through stages.
In the early stages, the cancer is found in the lining of the chest cavity, the lining of the lung or the lining of the abdominal cavity. In the advanced stages of mesothelioma, the cancer spreads beyond the lining of the chest or abdomen to lymph nodes, into the chest wall, center of the chest, heart, through the diaphragm, or abdominal lining. Eventually the mesothelioma may spread to distant organs or tissues.